Impaired Cognitive Performance Occurs Within Children With...

Background: Impaired cognitive performance occurs in children with multiple sclerosis (MS). In adults, cognitive impairment (CI) is seen at the time of first attack suggesting a prodrome of disease progression prior to first onset of physical disability. Children who develop multiple sclerosis also have CI at time of diagnosis suggesting that actual disease onset occurs prior to manifestation of physical symptoms. It has not been reported whether children who go on to develop a clinical diagnosis of multiple sclerosis are delayed in acquiring early developmental milestones. Objective: To determine whether children with early onset MS are delayed in attaining early developmental milestones and whether children with MS diagnosis prior to the age of 11 years are more likely to need special education services. Methods: Pediatric-onset MS and cases and controls less than 18 years of age from 14 pediatric MS centers in the United States were studied. A questionnaire on environmental and genetic influences was completed by family members, capturing information on demographic and developmental history. Data on time of first walking unaided and acquisition of two word phrases were captured on MS and control groups. The need for special education services was captured in MS subjects only. Results: A total of 467 cases and 428 controls were enrolled. Patients with early onset MS prior to age 18 were not delayed in walking or using two word phrases compared to healthy controls.Show MoreRelatedUnit 2 study guide8637 Words   |  35 Pagesclose, or open the gate. (p.482) 7. Know the type of nerve fibers that transmit pain impulses. Medium sized A delta fibers are stimulated by mechanical deformation (mechanonociceptors) and/or extremes of temperature(mechanothermal nociceptors) Occurs quickly. Carry well localized, sharp pain sensations and are important in initiating rapid reactions to stimuli (fast pain). Mechanical, thermal, and chemiacal nociception are transmitted by excitation of polymodal nociceptors and are carried onRead MoreHsc Level 5 Unit 534 Essay14626 Words   |  59 PagesCandidate Performance Evidence Record | | NVQ Title and Level: Health and Social Care level 5 Unit 534 †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦...... Candidate Name: Rafal Gac †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..................... Use this form to record details of activities (tick as appropriate) Observed by your assessor | | Professional discussion | | Evidence ref:Unit numbers: | Seen by an expert witness | | Product evidence observed | | | Seen by a witness | | Assignment/ ProjectOther__________________Read MoreChallenges Integrating Students With Disabilities6780 Words   |  28 Pagesas walking, seeing, breathing, working, and learning. Examples of disabilities listed in the federal regulations include, but are not limited to orthopedic, visual, speech and hearing impairments, cerebral palsy, epilepsy, muscular dystrophy, multiple sclerosis, cancer, heart disease, diabetes, emotional illness, specific learning disabilities, and HIV disease (Non-discrimination on the Basis of Disability in State and Local Government Services Final rule, 1991). Some disabilities commonly found among